NuBlocks LLC was established in 2005 in Oceanside, California. The company conducts custom synthesis and contract research with focus on nucleoside and nucleotide chemistry. NuBlocks has the expertise and capacity of manufacturing nucleoside analogs, their triphosphates and phosphoramidites. The company is well equipped to perform all kinds of chemical reactions such as low temperature, high pressure and hydrogenation reactions. NuBlocks has the extensive experience and equipment to conduct large scale chromatography purifications with silica gel, reverse phase and ion-exchange columns.