Nucleic Acid Experts

Nublocks specializes in custom nucleosides, nucleotides and phosphoramidite chemistry. We lead the way in synthesizing the building blocks for your unique research and drug development needs.

Services

Our Customers

Dedicated experts in research and synthesis of nucleobases

Starting in 2005, Nublocks was founded in California to provide high quality nucleosides and nucleotides for the use in drug development research. Initially offering custom phosphorylation and purification of nucleosides, it has since been expanded into over 1000 different nucleobase analogs. We create the buliding blocks for your mRNA solution so you can stay focused on effective drug discovery and delivery. We promise to never compromise on quality, delivery time and price. Our nucleoside phosphates have accelerated the drug research and discovery timeline of several global drug manufactuers. 

Illustration of builders constructing a DNA helix using various colored building blocks.

Extensive catalogue of custom synthesized nucleosides and nucleotides

With over 30 years of experience, we understand precision matters and will work closely with you to provide high purity nucleobase analogs for your RNA and DNA work. Let us discuss your project needs so our experts can tailor solutions that fit with your research goals. Time is of the essence we promise you regular updates and timely delivery of projects. Starting initially on phosphorylation of nucleosides to nucleoside triphosphates, we have expanded into a large catalogue of nucleoside analogs, custom nucleotides and phosphoramidite chemistry for oligonucleotides. Ready to elevate your DNA or RNA research for academia or industry drug discovery? Contact us today to learn how we can help.

DNA helix with other chemical molecules floating in space.

Wide range of services that suit your research needs

Nublocks offers a wide array of services whether you are a researcher or a pharmaceutical company. Our team designs and manufactures nucleotide analogs with modified bases or sugar whether your applications are enzyme inhibitor or antiviral.  We conduct custom synthesis and contracted research with a focus on nucleoside and nucleotide chemistry. Our synthetic nucleoside triphosphates (NTP) are actively in use by several global pharmaceutical companies and University research groups. Nublocks has the expertise to manufacture nucleoside analogs, their triphosphates and phosphoramidites with the capability of doing both small scale and large. Purification is another speciality of ours with numerous different columns and  refinery techniques to ensure your building blocks are of the highest quality. These purification requests can be done on large scale using a variety of silica gel, ion-exchange and reverse phase chromatography columns. Explore our services and contact us to let us know how we can help you.

Labratory picture of a custom synthesis utilizing vials and a pipette.
Science image with the Nublocks logo and text.
Our numbers

Decades of experience

Being in the business of nucleoside, nucleotide and phosphramidite chemistry for decades has established us with a wide range of products and customers.
0+
Years of experience
0+
Catalogued products
0+
Clients Helped